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Rovalpituzumab tesirine as a maintenance therapy after first-line platinum-based chemotherapy in patients with extensive-stagesclc: results from the phase 3 MERU Study

It downregulates the expression of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1), a master transcriptional regulator of mitochondrial genesis, through the microphthalmia-associated transcription factor (MITF) [19]

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Reproductive health research reveals significant applications in studying age-related endocrine dysfunction, with laboratory studies showing that FOXO4-DRI improves the testicular microenvironment and alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged male mice